Dall'improbabile e devastante impatto di un asteroide alle selvagge evoluzioni delle ere glaciali, fino agli eventi accidentali e unici che avvengono nelle gonadi dei nostri genitori, siamo tutti qui - noi e le altre specie animali e vegetali - come risultato di una serie sorprendente di avvenimenti fortunati. In un racconto che tiene insieme Jacques Monod e Charles Darwin, la geologia e la genetica, Kurt Vonnegut e gli stand up comedians, l'autore di "Infinite forme bellissime " Sean B. Carroll ci accompagna alla scoperta dell'incredibile potere del caso, e di come sia la fonte sorprendente di tutta la bellezza e la diversità del mondo vivente.

Gli esseri viventi esibiscono una straordinaria diversità di forme, dalle strisce della zebra ai disegni simmetrici sulle ali di una farfalla alle spirali della chiocciola. Come può una tale variegata modulazione di forme sbocciare da un grumo di cellule embrionali? Sean Carroll introduce con questo libro una nuova disciplina che ha fatto il suo ingresso nel panorama scientifico contemporaneo: l'Evo-Devo, abbreviazione di evolutionary developmental biology ("biologia evolutiva dello sviluppo"), una frontiera della ricerca in grado di interrogarsi sui rapporti tra sviluppo embrionale ed evoluzione delle specie. Prefazione di Telmo Pievani.

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? InThe Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon.

One of the most important revelations about the natural world is that everything is regulated--there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar--there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti rules to heal our ailing planet.

A bold and inspiring synthesis by one of our most accomplished biologists and gifted storytellers,The Serengeti Rules is the first book to illuminate how life works at vastly different scales--read it and you will never look at the world the same way again.

The never-before-told account of the intersection of some of the most insightful minds of the 20th century, and a fascinating look at how war, resistance, and friendship can catalyze genius.

In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, each joined the Resistance to help liberate the country from the Nazis, ascended to prominent, dangerous roles, and were very lucky to survive. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in their respective fields.

Drawing upon a wealth of previously unpublished and unknown material gathered over several years of research, Brave Genius tells the story of how each man endured the most terrible episode of the twentieth century and then blossomed into extraordinarily creative and engaged individuals. It is a story of the transformation of ordinary lives into exceptional lives by extraordinary events--of courage in the face of overwhelming adversity, the flowering of creative genius, deep friendship, and of profound concern for and insight into the human condition.

Since its inception, Introduction to Genetic Analysis has been known for its prominent authorship—leading scientists in their field who are great educators. This market best-seller exposes students to the landmark experiments in genetics, teaching students how to analyze experimental data and how to draw their own conclusions based on scientific thinking while teaching students how to think like geneticists.

La decifrazione del corredo genetico di numerosi animali, incluso l'uomo, e la loro analisi comparata hanno confermato senza ombra di dubbio le potenti intuizioni che portarono Darwin a elaborare la sua teoria sull'evoluzione della vita da un unico discendente comune. Il DNA, protagonista assoluto di "Al di là di ogni ragionevole dubbio", è da questo punto di vista un vero e proprio libro dove sta scritta la nostra storia, di individui e di specie, e dove sono contenuti gli indizi rivelatori della nostra diversità e di come essa si sia evoluta. Ma il libro del DNA è anche la prova scientifica definitiva in grado di confutare gli argomenti e la retorica di chi ancora si ostina a negare, di fronte all'evidenza dei fatti, la scienza dell'evoluzione. Carroll lo dice con chiarezza; è tutto scritto in questo "libro". Basta aprire alla prima pagina, e cominciare a leggere.

DNA is the genetic material that defines us as individuals. Over the last two decades, it has emerged as a powerful tool for solving crimes and determining guilt and innocence. But, very recently, an important new aspect of DNA has been revealed—it contains a detailed record of evolution. That is, DNA is a living chronicle of how the marvelous creatures that inhabit our planet have adapted to its many environments, from the freezing waters of the Antarctic to the lush canopy of the rain forest.

In the pages of this highly readable narrative, Sean Carroll guides the general reader on a tour of the massive DNA record of three billion years of evolution to see how the fittest are made. And what a eye-opening tour it is—one featuring immortal genes, fossil genes, and genes that bear the scars of past battles with horrible diseases. This book clinches the case for evolution, beyond any reasonable doubt.

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo-Evolutionary Developmental Biology-is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

Evo Devo is evolutionary developmental biology, the third revolution in evolutionary biology. The first was marked by the publication of The Origin of Species. The second occurred in the early twentieth century, when Darwin's theories were merged with the study of genetics. Now the insights of Evo Devo are astonishing the biology world by showing how the endless forms of animals—butterflies and zebras, trilobites and dinosaurs, apes and humans, are made and evolved.

Perhaps the most surprising finding of Evo Devo is the discovery that a small number of primitive genes led to the formation of fundamental organs and appendages in all animal forms. The gene that causes humans to form arms and legs is the same gene that causes birds and insects to form wings, and fish to form fins; similarly, one ancient gene has led to the creation of eyes across the animal kingdom. Changes in the way this ancient tool kit of genes is used have created all the diversity that surrounds us.

Sean Carroll is the ideal author to lead the curious on this intellectual adventure—he is the acknowledged leader of the field, and his seminal discoveries have been featured in Time and The New York Times.

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development.

• An accessible text, focusing on the most well-known genes, developmental processes and taxa.
  
• Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels.
  
• Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species.
  
• Provides in-depth focus on key concepts through well-developed case studies.
  
• Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary.
  
• Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.

An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.