Drug Transporters
Book (italiano):
<p>Understanding and quantifying the effects of drug transporters within the human body is essential for modulating drug safety and efficacy. This book comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. </p><p>The topics covered in this book ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical tools through to the potential impact of transporters in the clinic. Contributions are included from expert leaders in the field, at-the-bench industrial scientists, renowned academics and international regulators. Case studies and emerging developments are highlighted, together with the merits and limitations of the available methods and tools, and extensive references to reviews on specific in-depth topics are also included for those wishing to pursue their knowledge further.</p><p>As such, this text serves as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes. It will also serve as a reference tool on the models and calculations necessary to predict their effect on human pharmacokinetics and pharmacodynamics.</p>
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