Protein Deimination in Human Health and Disease
Book (italiano):
Deimination is a new post-translational modification of proteins, whose recognition is ever-increasing. First linked to the pathology of rheumatoid arthritis (RA), deimination is a process by which selected positively charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl arginine deiminase (PAD) family of enzymes. Although medical literature is rich with articles about the possible significance of deiminated proteins in RA, Protein Deimination in Ophthalmic and Neurological Health and Disease is the first publication to compile the growing amount of information now known about the presence of deiminated proteins in the eye and nervous system. Chronicling the earliest studies of deimination in the nervous system, up to the present, this volume distills what is currently known about citrullination of proteins in the eye and nervous system and is the first book of its kind on the topic.
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